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Glucagon-like-peptide-1 receptor expression in normal and diseased human thyroid and pancreas
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00:06:42 Vickie Danaher So generally speaking, efficacy seems pretty similar if we think about 9% more weight loss than placebo versus 11% more weight loss than with placebo, with oral semaglutide potentially having a very slight edge
Obesity disrupts bone metabolism and leads to increased bone resorption, but GLP-1RAs can inhibit this damage and improve bone health by increasing the OPG/RANKL ratio, reducing osteoclast activity, and promoting bone formation
That is understandable, but it is not the most important comparison
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